Excipients are the inactive substances used in medication to bulk out or house the active ingredients of the drug.This can help when the API is extremely potent and the dosage needs to be heavily controlled or if it needs help to be absorbed into the human body. Excipients come in tablet form for oral administration, and as a suppository for rectal administration. The medicines market is very competitive and companies keep the makeup of their excipients a secret so that their competitors do not find their secret for prolonging the shelf life.
GMP consulting is used by pharmaceutical companies to help them decide which ingredients to use in the excipients. Making your products different from your competitors will help you on the market as well as providing cost effective benefits.
Having a signature colour for your product can make it stand out from other drugs. It also makes it easier to identify your medicine by health care professionals and patients.
You can use flavourings to make your drugs taste better, like using a cherry flavouring in bitter products. You can also mask sour and salty flavours by using raspberry and apricots respectively.
Giving a longer shelf life to drugs is done by using preservatives. Synthetic preservatives like parabens can be used. If you want to use a natural substance, popular choices include vitamins A, E and C as well as citric acid.
Lubricants can be sourced from minerals like talk or from fats including vegetable fats and stearic acid which are most commonly used in tablets and hard gel capsules. They stop ingredients from sticking to the machinery and from clumping together during production.
Making drugs more manageable and practical to produce is why fillers are used. They need to be cost effective so they should be cheap, tasteless and also work well with the active ingredients in the drug.
Excipients need to do all these roles and more. Companies use GMP consulting to mark themselves out from their competitors. Consulting helps with keeping the products competitive but also ensures that they are safe for human use by checking that there will be no adverse side effects between the excipient and the API.
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